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PRP Therapy & Regenerative Medicine in Katy, TX

Harness your body's own healing power. Platelet-rich plasma therapy uses concentrated growth factors from your blood to accelerate healing in damaged joints, tendons, and ligaments.

What Is Platelet-Rich Plasma (PRP) Therapy?

Platelet-rich plasma (PRP) therapy is a regenerative treatment that uses concentrated healing factors from your own blood to stimulate tissue repair and reduce inflammation in injured or degenerated structures. The treatment is grounded in the fundamental biology of wound healing: when tissue is injured, platelets are among the first responders โ€” they aggregate at the injury site, activate, and release a cascade of growth factors that orchestrate the repair process. PRP amplifies this natural response by delivering a concentration 3โ€“8 times higher than normal blood platelet levels directly to the target tissue.

Dr. Qureshi performs all PRP injections under ultrasound or fluoroscopic guidance to ensure the concentrated growth factors are delivered precisely into the damaged structure. Because PRP uses your own blood, there is no risk of allergic reaction, disease transmission, or rejection.

The Science of PRP

Platelets contain hundreds of bioactive molecules stored in granules. When activated, platelets release a complex mixture including:

  • Platelet-Derived Growth Factor (PDGF) โ€” stimulates cell proliferation, angiogenesis, and extracellular matrix production
  • Transforming Growth Factor-Beta (TGF-ฮฒ) โ€” promotes collagen synthesis and tissue remodeling
  • Vascular Endothelial Growth Factor (VEGF) โ€” stimulates angiogenesis, improving blood supply to healing tissue
  • Insulin-Like Growth Factor 1 (IGF-1) โ€” promotes cell survival, proliferation, and matrix synthesis
  • Epidermal Growth Factor (EGF) โ€” stimulates cell growth and differentiation
  • Fibroblast Growth Factor (FGF) โ€” promotes proliferation of fibroblasts and endothelial cells

These growth factors collectively orchestrate the recruitment of mesenchymal stem cells and fibroblasts to the injury site, their proliferation, and their differentiation into new tissue-specific cells that synthesize collagen and other structural proteins needed to restore tissue integrity.

Conditions Treated with PRP

  • Knee osteoarthritis โ€” multiple high-quality randomized trials demonstrate PRP produces superior outcomes to corticosteroid and hyaluronic acid at 6โ€“12 months, with potential cartilage-protective effects
  • Hip and shoulder osteoarthritis โ€” growing evidence for intra-articular PRP as a longer-duration alternative to corticosteroid
  • Lateral epicondylitis (tennis elbow) โ€” one of the most evidence-based PRP indications; 2โ€“3 injection series produces superior long-term outcomes to corticosteroid across multiple RCTs
  • Rotator cuff tendinopathy โ€” PRP outperforms corticosteroid for partial rotator cuff tears and chronic tendinopathy in comparative studies
  • Patellar tendinopathy (jumper's knee) โ€” strong evidence for PRP combined with eccentric loading program
  • Achilles tendinopathy โ€” both insertional and mid-portion Achilles respond to PRP, particularly in chronic cases
  • Plantar fasciitis โ€” ultrasound-guided PRP provides significant improvement in chronic cases unresponsive to conservative measures
  • Sacroiliac joint dysfunction โ€” PRP for ligamentous laxity-related SI joint instability
  • Partial muscle tears โ€” Grade II hamstring, quadriceps, and calf tears respond to PRP-accelerated healing

The PRP Procedure: Step by Step

  1. Blood draw: 15โ€“60 mL of blood is drawn from a peripheral vein, similar to a standard lab draw
  2. Centrifugation: Blood is placed in a sterile centrifuge tube and spun at calibrated speed and duration to separate blood components by density
  3. PRP extraction: The platelet-rich layer is extracted under sterile conditions. Dr. Qureshi uses preparation protocols that yield appropriate platelet concentration and leukocyte content for the specific target tissue
  4. Guided injection: Under ultrasound or fluoroscopic visualization, Dr. Qureshi delivers the PRP precisely into the target structure โ€” confirming placement before injection
  5. Recovery: Brief observation, discharge instructions including activity modifications for the first 48โ€“72 hours, and follow-up scheduling

Expected Timeline and Results

PRP works through biological healing โ€” a gradual, durable process. Most patients experience:

  • Days 1โ€“5: Post-injection flare (increased soreness) as the healing cascade is initiated โ€” this is expected and normal
  • Weeks 2โ€“4: Beginning of gradual improvement as initial tissue repair commences
  • Weeks 4โ€“8: Meaningful improvement becoming apparent in most patients
  • Months 3โ€“6: Continued improvement as new tissue matures and remodels; peak effect typically at 3โ€“4 months
  • 12โ€“24 months: Long-term results consistently superior to corticosteroid in comparative studies

Frequently Asked Questions

Is PRP covered by insurance?
Most commercial insurance plans and Medicare currently classify PRP as investigational for musculoskeletal conditions and do not cover it. PRP is typically a self-pay treatment. Dr. Qureshi's office provides transparent upfront pricing. For many patients, the cost compares favorably to the cumulative expense of repeated corticosteroid injections, ongoing physical therapy, and ultimately surgical intervention that might be avoided with successful PRP treatment.
How many PRP injections do I need?
Most musculoskeletal conditions are treated with a series of 2โ€“3 PRP injections spaced 4โ€“6 weeks apart. Some patients experience meaningful improvement after a single injection. For joint arthritis, an annual maintenance injection is sometimes used once significant improvement is achieved. Dr. Qureshi will assess your response after the first injection and adjust the plan based on your individual reaction.
Should I avoid anti-inflammatory medications before or after PRP?
Many PRP protocols recommend avoiding NSAIDs (ibuprofen, naproxen, aspirin) for 1โ€“2 weeks before and 4โ€“6 weeks after injection because these medications suppress the inflammatory healing cascade that PRP relies on. Acetaminophen is typically acceptable for pain management post-injection. Dr. Qureshi will provide specific medication guidance based on the protocol used and your overall medication needs.
What is the difference between PRP and cortisone for joint pain?
Cortisone works quickly (3โ€“5 days) by suppressing inflammation, typically providing 4โ€“12 weeks of relief. It does not stimulate tissue repair. PRP works more slowly (peak effect at 2โ€“3 months) through active tissue regeneration, typically providing 6โ€“12+ months of relief with possible tissue-level healing. For acute inflammatory flares where rapid relief is needed, cortisone is often preferred. For longer-term management, PRP is increasingly the better choice.
Are there conditions where PRP should not be used?
PRP is generally contraindicated in active infection at the injection site, active cancer or hematologic malignancy, platelet dysfunction disorders, severe thrombocytopenia, and patients on anticoagulation that cannot be safely paused. Dr. Qureshi reviews your complete medical history before recommending PRP to ensure it is appropriate and safe for you.
Medical Disclaimer: This content is for educational purposes only and does not constitute medical advice. Individual results vary. Dr. Imran Qureshi, D.O. | 23501 Cinco Ranch Blvd, Suite G205, Katy, TX 77494 | (281) 982-2144

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